Modeling melanoma in reconstructed Human Skin

Elisabetta Michielon Thesis defense: 2024-09-11 Promotor: prof. dr. S. Gibbs and prof. dr. T.D. de Gruijl

On the TRAIL of a killer:

Mechanisms of action of an allogeneic NK cell therapy Amanda A. van Vliet Thesis defense: 1-7-2024 Promotor: prof. dr. S. Gibbs and prof. dr. T.D. de Gruijl

A nano-sized message:

Liposome-based vaccines for anti-tumor immunity Maarten K. Nijen Twilhaar Thesis defense: 25-4-2024 Promotor: dr. J.M.M. den Haan en prof. dr. G. Storm

NEUROIMMUNOLOGICAL MYSTERIES OF MULTIPLE SCLEROSIS

Immune cell dynamics in neurodegeneration Carla Rodriguez Mogeda Thesis defense: 12-3-2024 Promotor: prof. dr. H.E. de Vries, co-promotor prof. dr J. van Horssenand dr. M.E. Witte

Innocent until proven guilty

IgA and inflammation diseases Amelie Veerle Bos Thesis defense: 29-2-2024 Promotor: prof. dr. R. Mebius and prof.dr. M. van Egmond

Investigating local and systemic innate immune responses in skin and oral mucosa in vitro

Charlotte Rodriguez Neves Thesis defense: 11-12-2023 Promotor: prof. dr. S. Gibbs and prof.dr. T. Rustemeuer, co-promotor prof. dr. T. de Gruijl

Antibody therapy of cancer

Novel therapeutic strategies for prevention and treatment of metastases Mandy Gruijs Thesis defense: 20-09-2023 Promotor: prof. dr. van Egmond, co-promotor dr. N. Heemskerk

CD169 targeting liposomes

A cancer vaccine that delivers Joanna A. Grobowska Thesis defense: 5-06-2023 Promotor: prof. dr. Y. van Kooyk, dr. J.M.M. den Haan

Next generation organotypic human models to investigate gingiva, tooth, microbe and metal interactions

Yan Zhang Thesis defense: 21-06-2023 Promotor: prof. dr. S. Gibbs

Unravelling the Tumor Glyco -Code

Studying the role of glycosylation in cancer progression and immune evasion Juan Ernesto Rodriguez Camejo Thesis defense: 06-06-2023 Promotor: Prof.dr. Y. van Kooyk. Copromotor: Dr. J.J. Garcia Vallejo

Hypergranulatory tissue in breast implant surgery and skin scar formatio

Erik de Bakker Thesis defense: 24-02-2023 Promotor: Prof.dr. M. Ritt, prof.dr. S. Gibbs. Copromotor: Dr. F.B. Niessen

Microglia and beyond

Lynn van Olst Thesis defense: 24-02-2023 Promotor: prof. dr. H.E. de Vries, prof. dr. W.M. van der Flier. Copromotor: prof. dr. Ir. C.E. Teunissen, dr. M. E. Witte

An act of revision: IgA in health and disease

Melissa van Gool Thesis defense: 26-01-2023 Promotor: prof. dr. R. Mebius, prof. dr. M. van Egmond. Copromotor: dr. M. E. Witte

Targeting antigen presenting cells with lipid-based vaccines for the induction of strong immune responses

Dorian Stolk Thesis defense: 14-12-2022 Promotor: prof. dr. Y. van Kooyk, prof. dr. T.D. de Gruijl. Copromotor: prof. dr. J.J. van der Vliet

Surgery for colorectal cancer: a trigger for liver metastases development?

Simran Grewal Thesis defense: 27-10-2022 Promotor: prof. dr. M. van Egmond. Copromotor: dr. S.J. Oosterling

Rewiring the powerhouse. Macrophage metabolism in health and disease

Sanne Verberk Thesis defense: 21-10-2022 Promotores: prof. dr. H. E. de Vries, prof. dr. M. P. J. de Winther. Copromotor: dr. ir. J. Van den Bossche

The choroid plexus in progressive Multiple Sclerosis

Sabela Rodriguez Lorenzo Thesis defense: 21-4-2022 Promotor: prof. dr. H.E. de Vries. Co-pormotor: dr. G. Kooij

IgA – The art of balancing between host protection and auto-immunity

Annelot Breedveld Thesis defense: 1-7-2021 Promotores: prof. dr. M. van Egmond, prof. dr. R. Mebius

Glioblastoma immunotherapy. Catching an elusive tumour

Sophie Dusoswa Thesis defense: 29-6-2021 Promotor: prof. dr. Y. van Kooyk. Copromotor: dr. J.J. Garcia Vallejo

Dancing with dendritic cells: Targeting human skin dendritic cells for anti-tumor immunity

Sanne Duinkerken Thesis defense: 21-1-2021 Promotor: prof. dr. Y. van Kooyk. Copromotores: prof. dr. T.D. de Gruijl, dr. J.J. Garcia Vallejo

Aberrant cancer glycosylation: a potent regulator of tumor growth and anti-tumor immunity

Thanos Blanas Thesis defense: 12-1-2021 Promotor: prof. dr. Y. van Kooyk. Copromotor: dr. S.J. van Vliet

Passing a strong message: the IgA Fc receptor in health and disease

Marieke Heineke Thesis defense: 3-12-2020 Promotor: prof. dr. M. van Egmond. Copromotor: dr. J.E. Bakema

The Sweet Key to unlocking full dendritic cell potential

Eveline Li Thesis defense: 6-10-2020 Promotor: prof. dr. Y. van Kooyk. Copromotor: dr. S.J. van Vliet

Retinoic Acid in Immune Homeostasis

Martje Erkelens Thesis defense: 23-9-2020 Promotor: prof. dr. R. Mebius. Copromotor: prof. dr. M. van Egmond

Antigen delivery to dendritic cells: the route to induce anti-tumor T cell immunity

Sophie Horrevorts Thesis defense: 12-6-2020 Promotor: prof. dr. Y. van Kooyk. Copromotores: prof. dr. A.A. van de Loosdrecht, dr. S.J. van Vliet

Orchestrating the immune system to initiate adaptive anti-tumor immunity

Sjoerd Schetters Thesis defense: 15-5-2020 Promotor: prof. dr. Y. van Kooyk. Copromotores: dr. J.M.M. den Haan, dr. J. Van den Bossche

The keloid disorder. Histopathology and in vitro reconstruction

Grace Limandjaja Thesis defense: 12-3-2020 Promotor: prof. dr. S. Gibbs. Copromotores: dr. F.B. Niessen, prof. dr. R.J. Scheper

The multifaceted role(s) of astrocytes in the pathology of multiple sclerosis

Alwin Kamermans Thesis defense: 5-3-2020 Promotor: prof. dr. H.E. de Vries. Copromotores: prof. dr. J. van Horssen, dr. M. Rijnsburger

Vascular Involvement in Alzheimer’s Disease from bench to bedside

Ananya Chakraborty Thesis defense: 7-2-2020 Promotores: prof. dr. H.E. de Vries. prof. dr. W.M. van der Flier. Copromotor: R.D. Fontijn

Linking the sphingolipid profile and neuroinflammation in Alzheimer’s disease

Nienke de Wit Thesis defense: 7-2-2020 Promotores: prof. dr. H.E. de Vries. prof. dr. W.M. van der Flier. Copromotor: R.D. Fontijn

Interplay of CD169+ Macrophages and DCs: a game of give and take to induce anti-tumor T cell immunity

Dieke van Dinther Thesis defense: 27-6-2019 Promotor: prof. dr.Y. van Kooyk. copromotor: dr. J.M.M. den Haan

Biocompatibility and pharmalogical targeting. Possibilities for improving periotoneal dialysis

Karima Farhat Thesis defense: 24-1-2018 Promotor: prof. dr. Sue Gibbs. Copromotores: dr. C.J. Kleverlaan, dr. A.D. Bakker

Understanding endothelial cell behavior for regenerative medicine strategies

Hanneke Monsuur Thesis defense: 14-2-2018 Promotor: prof. dr. Sue Gibbs. Copromotores: dr. L.J. van den Broek, dr. P. Koolwijk

Oral wound healing and innate oral immune response studied in vitro

Jeroen Buskermolen Thesis defense: 24-1-2018 Promotor: prof. dr. Sue Gibbs. Copromotores: dr. C.J. Kleverlaan, dr. A.D. Bakker

FcαRI as therapeutic target to reduce IgA-induced neutrophil activation

Esil Aleyd Thesis defense: 2-7-2017 Promotores: prof. dr. M. van Egmond. Copromotor:: dr. J.E. Bakema

Cutaneous and oral wound closure in vitro; role of salivary peptides and cytokines

Mireille Boink Thesis defense: 22-5-2017 Promotor: prof. dr. S. Gibbs, prof. dr. E.C.I. Veerman. Copromotor: dr. J.G.M. Bolschers

Innate Lymphoid Cells in Human Peripheral Blood and Secondary Lymphoid Organs

Yotam Bar-Ephraïm Thesis defense: 7-3-2017 Promotores: prof. dr. R. Mebius. Copromotor:: dr. R. Reijmers

Manipulating macrophages: increasing the effectiveness in anti-cancer therapy

Rens Braster Thesis defense: 2-2-2017 Promotores: prof. dr. M. van Egmond, prof. dr. R.H.J. Beelen. Copromotor:: dr. G. Vidarsson

Anti-inflammatory interventions and biomarker identification in Peritoneal Dialysis

Evelina Ferrantelli Thesis defense: 6-10-2016 Promotores: prof. dr. R.H.J. Beelen, prof. dr. PM. ter Wee. Copromotores: dr. M.G. Vervloet, dr. F.J. van Ittersum

Reactive oxygen species in multiple sclerosis pathology

Jamie L. Lim Thesis defense: 8-9-2016 Promotores: prof. dr. H.E. de Vries, prof. dr. J. van Horssen

Inflammation at the blood-brain barrier. Implications for T cell migration into the brain in multiple sclerosis

Melissa A. Lopes Pinheiro Thesis defense: 14-4-2016 Promotor: prof. dr. H.E. de Vries. Copromotor: dr. W.W.J. Unger

Cellular and molecular mechanisms involved in scarless wound healing in the fetal skin

Mariëlle Walraven Thesis defense: 17-3-2016 Promotores: prof. dr. R.H.J. Beelen, prof. dr. M. van Egmond. Copromotor: dr. M.M.W. Ulrich

Role of Inflammation in Development of Atherosclerosis

Katka Szilagyi Thesis defense: 26-2-2016 Promotores: prof. dr. G. Kraal., prof. dr. M. de Winther. Copromotor: dr. T.K. van den Berg

Ischemic heart disease: From perfusion deficits after microvascular injury to perfusion restoration by arteriogenesis

Paul Teunissen Thesis defense: 16-12-2015 Promotor/copromotor: prof. dr. N. van Royen, prof. dr. A.J.G. Horrevoets, dr. P. Knaapen, M.P.J. de Winther

Normal versus hypertrophic wound healing: Does early inflammation determine final outcome?

Liselotte Butzelaar Thesis defense: 4-12-2015 Promotor/copromotores: prof. dr. R.H.J. Beelen, dr. F.B. Niessen, dr. M.M.W. Ulrich, A.B. Mink van der Molen

Immune modulation of bone marrow-derived cells in Ischemic Heart Disease

Cansu Yildirim Thesis defense: 4-11-2015 Promotor/copromotor: prof. dr. A.J.G. Horrevoets, dr. C.T.M. van der Pouw Kraan

Protection of the peritoneal membrane by active vitamin D in peritoneal dialysis

Andrea Stavenuiter Thesis defense: 8-10-2015 Promotor/copromotores: prof. dr. R.H.J. Beelen, prof. dr. P.M. ter Wee, dr. M.G. Vervloet

Human skin dendritic cells as target for anti-tumor vaccination

Cynthia Fehres Thesis defense: 2-7-2015 Promotores: prof. dr. Y. van Kooyk. Copromotor: dr. J.J. Garcia Vallejo

Astrocytes in multiple sclerosis associated neurodegeneration: a star is born

Philip Nijland Thesis defense: 2-4-2015 Promotor/copromotores: prof. dr. P. van der Valk, prof .dr. H.E. de Vries, dr. J. van Horssen

The Sweet and Sorrow of Pancreatic cancer: Galectin-4 and glycosylation in pancreatic cancer

Ana da Silva Aresta Belo van Wijk Thesis defense: 2-4-2015 Promotores: prof. dr. Y. van Kooyk. Copromotor: dr. I.M. van Die